Nutramax Reference Line

CalmRoot Blend

D

Evidence grade: D (41/100)

Weighted aggregate of each ingredient's strongest evidence (study quality × sample size). 3 ingredients.

Per-ingredient evidence

Ashwagandha

Strongest evidence: Case series / small trial, n=60

Case
GradenStudyFinding
Case60Ashwagandha root extract on stress and anxiety: randomized studyMedicine (Baltimore) · 2026-03-05Reduced perceived stress and serum cortisol over 8 weeks; small sample.

L-Theanine

Strongest evidence: Preclinical (in vitro / animal), n=0

Preclinical
GradenStudyFinding
Preclinical0L-theanine effects on stress and cognition: pilot trialNutrients · 2026-03-05Mechanistic and animal data on alpha-wave / GABA pathways; limited human data.

ProprietaryFocusBlend

Insufficient evidence — not graded (absence is not a negative score).

Insufficient

No indexed studies in the curated ledger for this ingredient. Predatory / non-indexed sources are excluded by design.

Not medical advice. Grades reflect the quality and quantity of published evidence for an ingredient — not a health claim, endorsement, or guarantee of effect. An absent study is reported as insufficient, never as proof a thing does or does not work. Talk to a clinician before changing any regimen.